Here is the list of some nice places (bars and clubs) in Prague for gay people:
Friends - Bartolomejska 11, Prague. One of the oldest and most established gay bars. Quite large with over 200 sqm, might be perfect for your first night. Excelent audio & video systems and airconditioning.
Saints - Polska 32, 12000 Prague 2, Vinorady. New club, not quite big but comfortable. Friendly stuff and relaxed atmosphere.
Tags: gay